Department of Public Expenditure, Infrastructure, Public Service Reform and Digitalisation

• Please provide a list of the top 10 ingredients (for example: "Adalimumab") in High‐Tech Drug Arrangement by cost, organised by calendar year for the last 5 years available. If the last 5 years available don't include 2023, please also include any available period for 2023 (for example the three first quarters). As part of the list, please indicate for each ingredient the overall costs and percentage of total expenditure. • Please provide a list of the top 20 drugs (for example: "Humira") in High‐Tech Drug Arrangement by cost, organised by calendar year for the last 5 years available. If the last 5 years available don't include 2023, please also include any available period for 2023 (for example the three first quarters). If the top 20 drugs are not available, please provide as many as possible. As part of the list, please indicate for each drug the overall costs and percentage of total expenditure. • Please provide the last five years available of "Review of High‐Tech Drug Expenditure". • Please also provide any paper, briefing, assessment, or document held by your department on the impact that high drug prices have on Ireland's budget and on access to treatment for Irish patients. You may limit your research to any document created after January 2019.